Table 1 Parameter values for the lactotroph model.
From: The dynamics underlying pseudo-plateau bursting in a pituitary cell model
Parameter | Value | Description |
|---|---|---|
C m | 5 pF | Membrane capacitance of the cell |
g Ca | 2 nS | Maximum conductance of Ca2+ channels |
V Ca | 50 mV | Reversal potential for Ca2+ |
ν m | -20 mV | Voltage value at midpoint of m∞ |
s m | 12 mV | Slope parameter of m∞ |
g K | 4 nS | Maximum conductance of K+ channels |
V K | -75 mV | Reversal potential for K+ |
ν n | -5 mV | Voltage value at midpoint of n∞ |
s n | 10 mV | Slope parameter of n∞ |
τ n | 43 ms | Time constant of n |
g K(Ca) | 1.7 nS | Maximum conductance of K(Ca) channels |
K d | 0.5 μ M | c at midpoint of s∞ |
g BK | 0.4 nS | Maximum conductance of BK-type K+ channels |
ν b | -20 mV | Voltage value at midpoint of f∞ |
s b | 5.6 mV | Slope parameter of f∞ |
f c | 0.01 | Fraction of free Ca2+ ions in cytoplasm |
α | 0.0015 μ M fC-1 | Conversion from charge to concentration |
k c | 0.16 ms-1 | Rate of Ca2+ extrusion |