Fig. 3

Effects of changes in the value of μ and k on the IPI and peak heights of Ca patterns generated by system (1a)–(1c). The values of μ and k corresponding to each colored pattern are given on the right of each panel. In a, the red signal is obtained with parameter values given in Table 1, the IPI equals 10 minutes and the height of the peaks is 342 nM (a dashed red line indicates this value in b, c, and d for the sake of comparison). b illustrates the effect of a change in μ on the IPIs: the blue (resp. green) pattern is obtained with a smaller (resp. larger) value of μ than the red pattern and has a smaller (resp. larger) IPI (7 minutes, resp. 14 minutes). c illustrates the effect of a change in k on the peak heights: an increase (resp. decrease) in the value of k, as in the blue (resp. green) pattern, implies a decrease (resp. increase) in both the height of the peaks (320 nM, resp. 365 nM) and the IPI (around 4.5 minutes, resp. 17 minutes). In d, we show how to hold the IPI constant (10 minutes) while obtaining a variability in the peak heights by changing k first (in the same way as in c) and then adjusting the value of μ