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Fig. 1 | The Journal of Mathematical Neuroscience

Fig. 1

From: M-Current Expands the Range of Gamma Frequency Inputs to Which a Neuronal Target Entrains

Fig. 1

Comparison between simulations of (1) with the M-current (panel A, \(g_{M}=1.5\) mS/cm2, \(I_{\mathit {ton}}=5\) μA/cm2) and without the M-current (panel B, \(g_{M}=0\) mS/cm2, \(I_{\mathit {ton}}=0.55\) μA/cm2), adjusted to have the same natural frequency (16 Hz). Top and bottom rows: Voltage trace of the I-cell is in blue. External gamma pulses (32 Hz) are in red. Middle row: M-current is in blue. Theta forcing is in red. In A (with the M-current), the spikes of the I-cell align with the external pulses. In B, the I-cell fails to follow the same pulses when the M-current is absent. The voltage envelope of the I-cell with M-current also has much less variation than the one without M-current. C: Simulation of (1) without M-current, but with the same excitability (34 Hz) at the peak of theta forcing as in A (\(g_{M}=0\) mS/cm2, \(I_{\mathit {ton}}=-1.7\) μA/cm2). One of the I-cell spikes during each theta cycle comes earlier than the external pulse

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