Table 1 Variables and parameters definitions
Variable or paremeter name | Definition |
|---|---|
E | Membrane potential |
m | Activation of fast sodium channels |
h | Inactivation of fast sodium channels |
\(m_{{s}}\) | Activation of slow sodium channels |
\(h_{{s}}\) | Inactivation of slow sodium channels |
n | Activation of potassium channels |
\(C_{{m}}\) | Equivalence membrane capacitance |
\(g_{{Naf}}\) | Fast sodium channels conductance |
\(g_{{k}}\) | Potassium channels conductance |
\(g_{{l}}\) | Leak channels conductance |
\(g_{ {NaS} }\) | Slow sodium channels conductance |
\(E_{{Na}}\) | Nernst potentials of fast sodium ions |
\(E_{{k}}\) | Nernst potentials of potassium ions |
\(E_{{l}}\) | Nernst potentials of leakage ions |
\(\alpha _{{m}}\) and \(\beta _{{m}}\) | Transition rates between open and closed states of the activation of sodium channels |
\(\alpha _{{h}}\) and \(\beta _{{h}}\) | Transition rates between open and closed states of the inactivation of sodium channels |
\(\alpha _{{n}}\) and \(\beta _{{n}}\) | Transition rates between open and closed states of the potassium channels |
\(\alpha _{{mS}}\) and \(\beta _{{mS}}\) | Transition rates between open and closed states of the activation of Slow sodium channels |
\(\alpha _{hS}\) and \(\beta _{hS}\) | Transition rates between open and closed states of the inactivation of slow sodium channels |