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Figure 2 | The Journal of Mathematical Neuroscience

Figure 2

From: A model of on/off transitions in neurons of the deep cerebellar nuclei: deciphering the underlying ionic mechanisms

Figure 2

Bifurcation analysis of the standard model with \(I_{\text{DC}}\) as the bifurcation parameter. A. Red: branch of stable fixed points (FP). Green: envelop (min and max) of a branch of stable limit cycles (sLC). Blue: envelop of a branch of unstable limit cycles (uLC). sLC and uLC appear as a fold of limit cycle (bifurcation \(F_{1}\)) and disappear in another fold of limit cycle (bifurcation \(F_{2}\)). Inset: amplitude (mV) of spikes corresponding to the branches of sLC and uLC. B. Firing frequency of stable and unstable spikes as a function of \(I_{\text{DC}}\). C. V (black) and [Ca] (red) trajectories following blocking of \(I_{\text{NaV}}\). D. The FP branch in the standard model (red) is altered by blocking \(I_{\text{NaV}}\) (green) and blocking \(I_{\text{NaV}}\) and \(I_{\text{TCN}}\) (blue)

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