Fig. 1
From: Uncertainty Propagation in Nerve Impulses Through the Action Potential Mechanism
a The top panel shows the probabilistic membrane potential, distributions are indicated by box-and-whiskers plots at each time instant. The middle panel shows the first order Sobol indices, revealing the sources of the fluctuations in the membrane potential for each uncertain parameter. The black line is the sum of all indices; deviation from one indicates variance due to parameter interactions. The bottom panel shows the variance difference w.r.t. the model with 11 uncertain parameters for four parsimonious models. Only two parameters (
and 
) are required to estimate a variability with less than 10 % error. b Average of the Sobol indices for all uncertain parameters during the time interval shown in a for the membrane potential and gating variables