Fig. 1
From: Modeling Focal Epileptic Activity in the Wilson–Cowan Model with Depolarization Block
Experimental data supporting the use of a Gaussian population response function during human seizure activity. A: Recording setup depicting the multi-electrode array situated in between the standard electrocorticography electrodes numbered 22, 23, 30, and 31. B: Example recordings of the low-frequency component of the local field potential (2–50 Hz, L-LFP, upper trace), the rectified signal filtered for spikes (300–3000 Hz, middle trace), and the integrated version thereof, using a leaky integrator with a 50 ms time constant (bottom trace) generating a firing rate index (FRI) for the multi-unit spike activity. The relationship between L-LFP and FRI is plotted in panel C; the error bars indicate SEM values