Fig. 3

Simulation of rhythmic sigh-like bursting in the Jasinski model. Simulation of rhythmic sigh-like bursting in the Jasinski model (1a)–(1g). From top to bottom: Time courses of membrane potential, calcium, sodium, total intracellular calcium concentration within the cell (\(\mathrm{Ca}_{\mathrm{tot}}\)) and \(\mathrm{IP}_{3}\) channel gating variable l. This SB pattern repeats periodically. The right panel provides a zoomed view showing the details of a regular small burst, where the dashed green and blue lines denote the end of a burst active phase and the beginning of the next such phase, respectively. Note the difference in time labels between the left and right panels