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Figure 3 | The Journal of Mathematical Neuroscience

Figure 3

From: Linking demyelination to compound action potential dispersion with a spike-diffuse-spike approach

Figure 3

Propagation Speed. Notice that the time scales are in milliseconds. (a) Filtered action potentials at distance \(X=0\) (red) and \(X=0.005\) (black), corresponding to \(d=1\text{ mm}\) and \(\lambda _{M} = 200\text{ mm}\). The threshold is shown in blue. Inset expands area in the gray rectangle. (b) The resulting speed of propagation (Eq. (11)) as a function of threshold θ. The blue dashed line indicates \(\theta ^{*}\), the parameter value used in the simulations. An average transmission delay of 0.0125 ms over \(d=1\text{ mm}\) yields a speed of 80 m/s. (c) Difference between latency distributions calculated from the action potential at \(X=0\) and \(X=0.005\) (shown in (a)) for \(\theta =20\) mV. Inset expands area in the gray rectangle. (d) Same as (c) but \(\theta =50\) mV

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